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TUMOR NECROSIS FACTORS
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DeCS
Descriptor
English
:
Tumor Necrosis Factors
Descriptor
Spanish
:
Factores de Necrosis Tumoral
Descriptor
Portuguese
:
Fatores de Necrose Tumoral
Tree Number:
D12.644.276.374.750
D12.776.467.374.750
D23.529.374.750
Definition
English
:
A
family
of
proteins
that were originally identified by their ability to cause
NECROSIS
of
NEOPLASMS
. Their necrotic effect on cells is mediated through TUMOR
NECROSIS
FACTOR RECEPTORS which induce
APOPTOSIS.
History Note
English
:
2005
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
38737
Unique Identifier:
D048069
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS